DREAM 6 – Alternative Splicing Challenge
Learn More The goal of the mRNA-seq alternative splicing challenge is to assess the accuracy of the reconstruction of alternatively spliced mRNA
DREAM 6 – Estimation of Model Parameters Challenge
Learn More Given the complete model structures (including expressions for the kinetic rate laws) for three gene regulatory networks, participants are asked
DREAM Gene Expression Prediction Challenge
Learn More Predict gene expression levels from promoter sequences in eukaryotes
DREAM 5 – Epitope-Antibody Recognition (EAR) Challenge
Learn More Humoral immune responses are mediated through antibodies. About 1010 to 1012 different antigen binding sites called paratopes are generatedby genomic
DREAM 5 – Transcription-Factor, DNA-Motif Recognition Challenge
Learn more Transcription factors (TFs) control the expression of genes through sequence-specific interactions with genomic DNA. Different TFs bind preferentially to different
DREAM 4 – Peptide Recognition Domain (PRD) Specificity Prediction
Learn More Many important protein-protein interactions are mediated by peptide recognition domains (PRD), which bind short linear sequence motifs in other proteins.
DREAM 3 – Signaling Response Prediction
Learn More Approximately 10,000 intracellular measurements (fluorescence signals proportional to the concentrations of phosphorylated proteins) andextracellular measurements (concentrations of cytokines released in
DREAM 4 – Predictive Signaling Network Modelling
Learn More This challenge explores the extent to which our current knowledge of signaling pathways, collected from a variety of cell types,
DREAM 3 – Gene Expression Prediction
Read More Gene expression time course data is provided for four different strains of yeast (S. Cerevisiae), after perturbation of the cells.