DREAM 5 – Systems Genetics Challenge
Learn More The central goal of systems biology is to gain a predictive, system-level understanding of biological networks. This can be done,
DREAM Gene Expression Prediction Challenge
Learn More Predict gene expression levels from promoter sequences in eukaryotes
DREAM 5 – Epitope-Antibody Recognition (EAR) Challenge
Learn More Humoral immune responses are mediated through antibodies. About 1010 to 1012 different antigen binding sites called paratopes are generatedby genomic
DREAM 5 – Transcription-Factor, DNA-Motif Recognition Challenge
Learn more Transcription factors (TFs) control the expression of genes through sequence-specific interactions with genomic DNA. Different TFs bind preferentially to different
DREAM 5 – Network Inference Challenge
Learn More The goal of this Network Inference Challenge is to reverse engineer gene regulatory networks from gene expression datasets. Participants are
DREAM 4 – Peptide Recognition Domain (PRD) Specificity Prediction
Learn More Many important protein-protein interactions are mediated by peptide recognition domains (PRD), which bind short linear sequence motifs in other proteins.
DREAM 4 – In Silico Network Challenge
Learn More The goal of the in silico network challenge is to reverse engineer gene regulation networks from simulated steady-state and time-series
DREAM 3 – Signaling Response Prediction
Learn More Approximately 10,000 intracellular measurements (fluorescence signals proportional to the concentrations of phosphorylated proteins) andextracellular measurements (concentrations of cytokines released in
DREAM 4 – Predictive Signaling Network Modelling
Learn More This challenge explores the extent to which our current knowledge of signaling pathways, collected from a variety of cell types,
DREAM 3 – Gene Expression Prediction
Read More Gene expression time course data is provided for four different strains of yeast (S. Cerevisiae), after perturbation of the cells.