Approximately 10,000 intracellular measurements (fluorescence signals proportional to the concentrations of phosphorylated proteins) andextracellular measurements (concentrations of cytokines released in response to cell stimulation) were acquired in human normal hepatocytes andthe hepatocellular carcinoma cell line HepG2 cells. The datasets consist of measurements of 17 phospho-proteins (at 0 min, 30 min, and 3 hrs)and 20 cytokines (at 0 min, 3 hrs, and 24 hrs) in two cell types (normal and cancer) after perturbations to the pathway induced by thecombinatorial treatment of 7 stimuli and 7 selective inhibitors. More info
admin2021-03-09T19:33:43+00:00March 9, 2009|Categories: Challenges|Tags: Method Optimization, Protein Concentration|