October 2, 2014


July 8, 2015

Applied Knowledge Building networks for translation: how to use DREAM challenges and the Synapse platform as a research strategy

A special session at  the ISMB/ECCB Conference in Dublin, Ireland on July 11 will explain the rationale behind running a DREAM Challenge, the steps involved from both sides of the process (organizers and participants), the lessons learned, and the potential uses of DREAM Challenges in education. A hands-on exercises with the Synapse platform will also be featured. (Read more.)

June 23, 2015

Prize4Life, Sage Bionetworks and DREAM Launch an Open Science Challenge

The  DREAM Challenge goals is to find clues to understanding heterogeneity in patients with Amyotrophic Lateral Sclerosis (ALS).  The DREAM ALS Stratification Prize4Life Challenge brings together patients, clinical researchers, data scientists and pharmaceutical industry leaders to computationally identify for the first time different subgroups of ALS patients, to pave the way for potential new treatments.  (read more)

May 18, 2015

Research community comes together to provide new ‘gold standard’ for genomic data analysis

Cancer research leaders at the Ontario Institute for Cancer Research, Oregon Health & Science University, Sage Bionetworks, the distributed DREAM (Dialog for Reverse Engineering Assessment and Methods) community and The University of California Santa Cruz published the first findings of the ICGC-TCGA-DREAM Somatic Mutation Calling (SMC) Challenge today in the journal Nature Methods. (Read more).

April 29, 2015

Probing The Realities of Big Data In Alzheimer’s

Still Alice, the film with Academy-award winning actress Julianne Moore, powerfully depicts a woman’s steep descent into Alzheimer’s Disease (AD) and demonstrates why people overwhelmingly cite Alzheimer’s as the disease they most fear. (Read more)

April 7, 2015

Cancer: smoother journeys for molecular data

Cancer ‘omics data sets are now available in all sizes, especially XXL, thanks to large-scale tumor-genome sequencing efforts and the transcriptomic, epigenomic and proteomic characterization of thousands of tumors. These data help scientists decipher molecular mechanisms involved in tumor formation and cancer progression. (Read more)

March 16, 2015

Oncologist: Editorial – The Prostate Cancer DREAM Challenge

The Prostate Cancer DREAM Challenge: A Community-Wide Effort to Use Open Clinical Trial Data for the Quantitative Prediction of Outcomes in Metastatic Prostate Cancer.  Massive quantities of digital health care data have been generated over the past 10 years and are the perfect catalyst to foster an open ecosystem in medical research. (Read More)

March 2, 2015

Beneficial Stats

Statisticians who normally crunch numbers to forecast trends in the food-service industry turn their attention to bettering treatment of ALS. (Read more)

January 28, 2015

Predicting Cancer Drug Response: Advancing the DREAM

The DREAM challenge is a community effort to assess current capabilities in systems biology.Two recent challenges focus on cancer cell drug sensitivity and drug synergism, and highlight strengths and weaknesses of current approaches. (Read more)