October 2, 2014
  • Question. Collaborate. Contribute.

DREAM Challenges pose fundamental questions about systems biology and translational medicine. Designed and run by a community of researchers from a variety of organizations, our challenges invite participants to propose solutions — fostering collaboration and building communities in the process. Expertise and institutional support are provided by Sage Bionetworks, along with the infrastructure to host challenges via their Synapse platform. Together, we share a vision allowing individuals and groups to collaborate openly so that the  “wisdom of the crowd” provides the greatest impact on science and human health.


Eduati F, Mangravite LM, et al; Prediction of human population responses to toxic compounds by a collaborative competition; Nature Biotechnology (2015) doi:10.1038/nbt.3299  


Learn more about the science of the DREAM Challenges in our latest video produced at the 2015 DREAM Conference in Philadelphia.  


DREAM 9.5 Prostate Cancer DREAM Challenge

Final results available. »more

DREAM 9.5 -DREAM Olfaction Prediction Challenge

Final results available. »more  
May 18, 2016

Challenges: Crowdsourced solutions

A commentary in the most recent issue of the journal Nature discusses how DREAM Challenges and other open competitions bring new minds, skills and collaborations to problems in biomedical research. (Read More)

November 17, 2015

International team launches community competition to understand tumor origins and evolution

An international consortium of groups from Canada, the United States and the United Kingdom have come together to create an innovative, cloud-based, public challenge running on the Google Cloud Platform to optimize the discovery of genetically distinct groups of cells within cancers that could respond differently to treatment and have different risk of spreading. (Read more)