DREAM Challenges


challenges that appear on the homepage AND the open page

  • COVID-19 EHR DREAM Challenge

    COVID-19 EHR DREAM Challenge

    The rapid rise of COVID-19 has challenged healthcare globally. Due to the importance and emergent need for better understanding of the condition and the development of patient specific clinical risk scores and early warning tools, we have developed a platform to support testing analytic and machine learning hypotheses on clinical data without data sharing as a platform to rapidly discover and implement approaches for care. This Challenges aims to identify risk factors that lead to a positive test utilizing electronic health recorded data mapped to the OMOP Common Data Model. REGISTER NOW

  • CTD^2 Pancancer Chemosensitivity DREAM Challenge

    CTD^2 Pancancer Chemosensitivity DREAM Challenge

    Current round: Pre-competition
    Registration Open: April 20, 2020
    Webinar: April 28, 2020 Click here for attendance options.
    Launch: April 28, 2020
    Leaderboard Round Opens: April 28, 2020
    Leaderboard Round Closes: June 29, 2020, 5PM Pacific Time
    Final Round Opens: June 29, 2020, 5PM Pacific Time
    Final Round Closes: July 27, 2020, 5PM Pacific Time
    Winners Announced: August, 2020

    The goal of this Challenge is to foster development and benchmarking of algorithms to predict the sensitivity, as measured by the area under the dose-response curve, of a cell line to a compound based on the baseline transcriptional profiles of the cell line.

  • Metadata Automation DREAM Challenge

    Metadata Automation DREAM Challenge

    Open Phase: Ends 2/9/2020
    Webinar: 1/30/2020
    Leaderboard Phase Round 1: 2/10/2020 - 3/9/2020
    Leaderboard Phase Round 2: 3/10/2020 - 4/9/2020
    Validation Phase: 4/10/2020 - 4/24/2020
    Winners Announced: early May 2020

    We aim to significantly lower the burden of adding coherent metadata annotations across the data ecosystem to streamline and enable both retrospective harmonization as well as data query, discovery and interpretation. This challenge addresses this time-consuming task with automated metadata annotation of structured data.

  • CTD^2 Beat AML DREAM Challenge

    CTD2 Beat AML DREAM Challenge

    Open Phase: Ends 1/6/2020
    Webinar: 1/6/2020 11:00 AM PST
    Leaderboard Phase: 1/6/2020 - 3/2/2020
    Validation Phase: 3/2/2020 - 4/28/2020
    Winners Announced: early May 2020

    The goal of the Beat AML DREAM Challenge is to define patient subpopulations tailored to individual treatments by discovering (genomic and transcriptomic) biomarkers of drug sensitivity, as evaluated on an unpublished cohort of patients from the BeatAML project.


  • RA2 DREAM Challenge

    RA2 DREAM Challenge: Automated Scoring of Radiographic Joint Damage

    Launch: November 4, 2019 (Now open)
    Final Submissions: May 31, 2020
    Winners Announced: July 31, 2020

    Rheumatoid Arthritis (RA) is a debilitating disease that causes joint damage in the hands and feet due to inflammation. Accurate measuring of joint damage and progression of disease is essential in assessing the severity of disease, along with being able to monitor patient response to treatment. Scoring of X-ray images is tedious and there can be a great deal of variability between rheumatologists when applying scoring methods. We will leverage nearly 1000 images across a range of disease severities to challenge participants to develop an automated scoring algorithm with the goal of making clinical scoring fast and consistent; this will aid rheumatologists in making the best decisions for patients.


  • Tumor Deconvolution DREAM Challenge

    Tumor Deconvolution DREAM Challenge

    Launch:  June 3, 2019 (Challenge Now Open!)
    Webinar: June 5, 2019

    The goal of this Challenge is to evaluate the ability of computational methods to deconvolve bulk expression data, reflecting a mixture of cell types, into individual immune components.